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The use in disturbances of the female alternative genital system was first reported more than two thousand years ago. Nowadays ethanolic extracts medicine from the fruit are used for the treatment of mastopathy, premenstrual syndrome and luteal insufficiency-complaints caused by a mild or latent hyperprolactinemia. The mode of action of Vitex agnus-castus extracts was studied in vitro review using alternative primary cultures from rat pituitaries as a test system. A dose dependent reduction of prolactin secretion was observed. The effect could be blocked by the dopamine-receptor antagonist, haloperidol, confirming a dopamine agonistic activity of the drug. The prolactin lowering medicine effect of Vitex agnus-castus was also found review in in vivo experiments in rats. Clinical studies in patients with premenstrual syndrome, luteal insufficiency, and mastopathy show a simultaneous decrease in the clinical syndrome score and prolactin levels. In the monograph of the Commission E, a daily dosage of 30-40mg of an ethanolic extract of the fruit of Vitex agnus-castus is recommended for the treatment of the premenstrual syndrome, luteal phase defects and other disturbances of the menstrual cycle, as well for the treatment of mastodynia . The rest degenerate over the years. During the reproductive years, a gland in the brain generates hormones that cause a new egg to be released from its follicle each month. As the follicle develops, it produces the sex hormones estrogen and progesterone, which thicken the lining of the uterus. This enriched lining is prepared to receive and nourish a fertilized egg, which could develop into a baby. If fertilization does not occur, estrogen and progesterone levels drop, the lining of the uterus breaks down, and menstruation occurs. For reasons unknown, your ovaries gradually begin alternative to medicine decline in hormone production review during your mid-30s. In your late 40s, the process accelerates and hormones fluctuate more, causing irregular menstrual cycles and unpredictable episodes of bleeding. By your early to mid-50s, periods finally end altogether. However, estrogen production does not completely stop. The ovaries alternative decrease their output significantly, but still may produce a small amount. Progesterone, the other female hormone, works during the second half of the menstrual cycle to create a lining in the uterus as a viable home for an egg, and to shed the lining if the egg is not fertilized. These women, as well as women who experience early natural menopause (before age 40) or prolonged time without menstrual periods due to excessive exercising or dieting, may be at a greater risk later in life for health problems such medicine as osteoporosis or early heart disease because they spend more years without the protective effect of estrogen. Just as every womanıs body is unique, review your menopause experience will be a highly personal one. For example, 15 to 20 percent of women experience no physical symptoms at all, except the end of their menstrual periods. Some women go through menopause before age 51 and some experience it a bit later. Early menopause is defined as occurring at any age younger than age 51. Early menopause can occur naturally, but premature menopausal symptoms may signal an underlying condition, so it is important to discuss any symptoms alternative with your medicine healthcare professional. Menopause can occur as early as your 30s and, rarely, as late as in your 60s. However, there is no correlation between the time of a woman''s first period and her age at menopause. In addition, age at menopause is review not influenced by race, height, the number of children a woman has had,
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